Glossary
Coupled Transcription- Translation
Scaffold/matrix attachment regions (S/MARs
Systemic Lupus Erythematosus (SLE)
Chromosomes of same length and have genes in exactly same location or locus.
The DNA sequence on to which the proteins and enzymes involved in transcription bind .to initiate the process of transcription
The short arm of the chromosome
The long arm of chromosome
These are the protein coding sequences of mRNA
Also called non coding strand . It is the DNA strand which acts as template for transcription
A nucleosome plus histone H1
The process of turning on a gene to produce RNA and protein
The processing of the RNA involving the removal of introns and ligation of exons
These are alternative forms of a gene. Differences in alleles account for the considerable genetic variation among people.
Sex chromosome
Non bacterial prokaryotes that share many similarities with eukaryotes
Body Chromosomes
Cancer of the lymph system caused due to aberrant expression of Myc protein
The process of Transcription and Translation occuring simultaneously.
Regulatory proteins that regulate various phases of cell cycle.
These are binding sequences for transcription factors and may be located upstream or down stream of transcription start site
The basic proteins rich in lysine and arginine and bind with the DNA
Active enzyme comprising of an enzyme and its coenzyme
These are genes expressed in all cells at all time
These are the intervening , non coding sequences of m RNA
State that the consensus sequence 5' -gccRccAUCC-3' must appear around AUG of vertebrate genes. Sequences closer to this consensus show higher efficiency of translation
Otherwise called as non coding strand .. This DNA strand does not serve as template for transcription
Genes that encode for enzymes with related functions are clustered together and regulated together. This organization of genes is called an Operon
m RNAs containing the information to make more than one proteins . Prokaryotes have Polycistronic mRNA
Genes when mutated that can become Oncogenes and cause cancer
Chronic inflammatory autoimmune skin disease
Auto reactive immune cell mediated inflammatory condition primarily affecting the joints
DNA sequences that interact with proteinaceous nuclear scaffold
The nucleotide sequence located 8-10 nucleotides upstream of the start codon.Interaction between the complementary anti-SD sequence in 16S ribosomal RNA recruits 30S ribosomal subuni at the correct location on the m RNA
Multi-organ involved auto immune disease causing inflammation and tissue damage in the affected organs .
Disease characterized by autoimmune cells mediated damage of the connective tissue
The molecular process by which the information in DNA is copied in to RNA. This process is carried out in the nucleus of the cell
The process by which the information in mRNA is decoded forming protein. This is carried out in the cytoplasm of the cell
